Postdoctoral Research Associate in Solute Carrier structural biology/Drug Design

**Pay Scale:** STANDARD GRADE 7



**Salary ( £)**: £39,347 - £40,521 per annum



**Location:** Department of Biochemistry, South Parks Road, Oxford



**Contract type:** Fixed Term



**Hours:** Full-time





**About the role**





We are seeking to appoint a Postdoctoral Research Associate to join Prof Simon
Newstead’s lab in collaboration with Prof Philip Biggin (Oxford Biochemistry)
and Prof Chris Schofield (Oxford Chemistry) to develop a computational
pipeline to help design antibiotics with improved uptake into humans. This
builds on a substantial body of work already performed by this team using a
combination of advanced structural biology, computational techniques, and
chemical synthesis. The aim of this post is to establish the mechanistic rules
for proton coupling in Peptide Transporters and explore the development of
inhibitors and modulators.





This full-time fixed-term post is funded by the BBSRC for up to 3 years in the
first instance.





The actual starting salary offered will be based on qualifications and
relevant skills acquired and will also be determined by the funding available.





**What We Offer**





Your happiness and wellbeing at work matters to us, so we offer a range of
family friendly and financial benefits including:





• An excellent contributory pension scheme



• 38 days annual leave



• A comprehensive range of childcare services



• Family leave schemes



• Cycle loan scheme



• Membership to a variety of social and sports clubs



• Discounted bus travel and Season Ticket travel loans





The University also runs an enormous amount of social groups and sports clubs
for those looking for more than just a great place to work.





**About you**





The successful applicant will work closely with the computational scientist
employed in Prof Biggin’s lab to develop a computational pipeline for
improving antibiotic transport. Chemical synthesis support will be provided by
colleagues in Prof Schofield’s laboratory. The PDRA will therefore be expected
to work very closely with PDRAs in our collaborator laboratories.





You will possess a PhD/DPhil or be near completion of a PhD/DPhil in
Biochemistry, Structural Biology, Chemistry or related subject.





You are expected to have previous experience with eukaryotic membrane protein,
as well as in mammalian or insect recombinant expression systems. You should
be able to demonstrate competence and success in your thesis research (and
postdoctoral work if appropriate). Excellent communications skills, the
ability to write for publication and present research proposal results and
results is also essential. You will also have demonstrable skills in teamwork.





**Application Process**





You will be required to upload a supporting statement, setting out how you
meet the selection criteria, curriculum vitae and the names and contact
details of two referees as part of your online application.





Only applications received before **12 noon** on **Tuesday 6th August 2024**
can be considered with interviews for shortlisted candidates to be held as
soon as possible thereafter.



**Committed to equality and valuing diversity**