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All vacancies within Department of Physiology, Anatomy and Genetics (DPAG)

There are currently 4 vacancies within Department of Physiology, Anatomy and Genetics (DPAG):

Title Closes Salary
Postdoctoral Research Scientist in Neuroscience May 23, 2022, noon not specified
Postdoctoral Research Scientist in Neuroscience May 23, 2022, noon not specified
Postdoctoral Research Scientist: lymphatic vessel-immunomodulation following heart injury June 1, 2022, noon Standard Grade 7: £33,309 - £40,927
Post-doctoral Research Scientist in dopamine and astrocyte biology in health and Parkinson's disease June 6, 2022, noon Standard Grade 7: £33,309 - £40,927

Postdoctoral Research Scientist in Neuroscience

Closes: May 23, 2022, noon; salary: not specified

<div> <p></p><div><strong>Department of Physiology, Anatomy &amp; Genetics</strong></div><br> <div><strong>University of Oxford</strong></div><br> <div>Sherrington Building, Parks Road, Oxford</div><br> <div>&#160;<br> <br>&#160;</div><br> <div><strong>Postdoctoral Research Scientist</strong></div><br> <div><strong>Salary Grade 7: &#163; 33,309 - &#163;40,927</strong></div><br> <div><strong>Available from 1 November 2022</strong></div><br> <div><strong>Fixed Term until 30 September 2024</strong></div><br> <div>&#160;</div><br> <div>Applications are invited for a Postdoctoral Research Scientist to join the lab of Professor Gero Miesenboeck at the Centre for Neural Circuits and Behaviour at the University of Oxford to work on a project that seeks to understand why we need to sleep by studying how the brain responds to sleep loss.</div><br> <div>&#160;</div><br> <div>Duties include synthesis of fly stocks, construction and validation of vectors for expression of transgenes, genotyping of transgenic fly stocks, brain dissection and immunostaining, two-photon microscopy, whole-cell patch-clamp recording, analysis of sleep behaviour, learning and memory and project management including analysing data and keeping accurate records of all experiments. &#160;</div><br> <div>&#160;</div><br> <div>You will also be responsible for managing your own academic research and administrative duties, contribute ideas for new research projects, develop ideas for generating research income, collaborate in preparing of scientific reports and journal articles and act as a source of information for other members of the group.</div><br> <div>&#160;</div><br> <div>You will hold or be close to completion of a PhD in Biological sciences with a specialisation in Neuroscience by November 2022 and have extensive research experience in neuronal cell biology, synaptic transmission as well as experience in electrophysiology, immunostaining and optical microscopy.</div><br> <div>&#160;</div><br> <div>The post holder will work in the group led by Professor Miesenboeck and will be based at the Centre for Neural Circuits and Behaviour, Tinsley Building, Mansfield Road, Oxford, OX1 3TA.</div><br> <div>&#160;</div><br> <div>This is a full time, fixed term post available until September 2024 and is funded by the European Research Council.&#160; Owing to the nature of this position, any offer of employment with the University will be subject to a satisfactory security screening. &#160;</div><br> <div>&#160;<br> <br>&#160;</div><br> <div>Closing date for applications is 12 Noon on 23 May 2022.&#160;</div><br> <div>&#160;</div><br> <div>Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.</div><br> <div>&#160;</div><br> <div>We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. &#8211; DPAG Statement of Inclusion</div> </div>

Postdoctoral Research Scientist in Neuroscience

Closes: May 23, 2022, noon; salary: not specified

<div> <p></p><div>&#160;&#160;</div><br> <div><strong>Postdoctoral Research Scientist in Neuroscience</strong></div><br> <div><strong>Salary Grade 7: &#163; 33,309 - &#163;40,927</strong></div><br> <div><strong>Available from 1 November 2022</strong></div><br> <div><strong>Fixed Term until 30 November 2026</strong></div><br> <div>&#160;</div><br> <div>Applications are invited for a Postdoctoral Research Scientist to join the lab of Professor Gero Miesenboeck at the Centre for Neural Circuits and Behaviour at the University of Oxford to work on a project that will seek to understand why we need to sleep and what drives sleep need by studying genetically modified mouse models and their sleep phenotypes as well as underlying mechanisms.</div><br> <div>&#160;</div><br> <div>Duties will include breeding and maintenance of mouse models, genotyping of transgenic mouse models, behavioural assays including analysis, Two-photon microscopy, confocal imaging and electrophysiology.</div><br> <div>&#160;</div><br> <div>You will also be responsible for managing your own academic research and administrative duties, contribute ideas for new research projects, develop ideas for generating research income, collaborate in preparing of scientific reports and journal articles and act as a source of information for other members of the group. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.</div><br> <div>&#160;</div><br> <div>You will hold or be close to completion of a PhD or MD in Biological Sciences or Medicine with a specialisation in Neuroscience by November 2022 and have excellent practical experience of working with mouse models. &#160;You will have extensive research experience in mouse neurobiology, molecular biology and mouse genetics and data analysis and visualisation.&#160; You will have experience in electrophysiology, immunostaining and imaging and behavioural assays.&#160;</div><br> <div>&#160;</div><br> <div>The post holder will work in the group led by Professor Miesenboeck and will be based at the Centre for Neural Circuits and Behaviour, Tinsley Building, Mansfield Road, Oxford, OX1 3TA.</div><br> <div>&#160;</div><br> <div>This is a full time, fixed term post available until 30 November 2026 and is funded by the Medical Research Council.&#160; Owing to the nature of this position, any offer of employment with the University will be subject to a satisfactory security screening. &#160;</div><br> <div>&#160;<br> <br>&#160;</div><br> <div>Closing date for applications is 12 Noon on Monday 23 May 2022.</div><br> <div>&#160;<br> <br>&#160;</div><br> <div>Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.</div><br> <div>&#160;</div><br> <div>We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. &#8211; DPAG Statement of Inclusion</div> </div>

Postdoctoral Research Scientist: lymphatic vessel-immunomodulation following heart injury

Closes: June 1, 2022, noon; salary: Standard Grade 7: £33,309 - £40,927

<div> <p></p><div><strong>Full time, fixed term post Grade 7: &#163;33,309- &#163;40,927 per annum</strong></div><br> <div>&#160;</div><br> <div>Applications are invited for a postdoctoral research scientist to work with Professor Paul Riley on a Medical Research Council-funded programme of research in which the overarching goal is to understand how the cardiac lymphatic vasculature can be fully exploited to modulate the immune response and optimize outcome after cardiac injury.</div><br> <div>&#160;</div><br> <div>The successful applicant will work closely with the Riley group to gain insight from mouse models of lymphatic-based immune cell trafficking during adult heart injury; exploiting surgical models of heart attack, lineage-specific cell fate mapping with histology and confocal microscopy. They will also perform multi-omics at single cell resolution, combined with targeted qPCR and cytokine arrays to characterize the activated lymphatic endothelium and to molecularly phenotype retained versus cleared immune cells. These analyses will be combined with functional magnetic resonance imaging (MRI) to determine optimal spatio-temporal clearance and to define which immune cell sub-populations are beneficial or detrimental for improved outcome following heart attack (myocardial infarction).</div><br> <div>&#160;</div><br> <div>The Postdoc will work closely with a second group member on the same programme focusing on modelling human lymphangiogenesis for drug discovery.</div><br> <div>&#160;</div><br> <div>Responsibilities will include managing academic work and administrative duties, generating high quality data, adapting and developing scientific techniques and experimental protocols, and contributing ideas for new research projects. You will be required to use specialist scientific equipment in a laboratory environment, and to act as a source of information and advice to members of the group on scientific protocols and experimental techniques as well as assist in training and supervising students within the group. In addition, you will be expected to present at scientific meetings and contribute to drafting manuscripts for the publication of your studies.</div><br> <div>&#160;</div><br> <div>You will hold, or be near the completion of, a relevant PhD/DPhil, and have relevant experience in molecular/cellular biology relevant to the project. In addition, you must have the ability to contribute significant intellectual input to the progress and direction of the research project, and the ability to take the lead in some areas. You must be strongly motivated with a highly enthusiastic approach to science with good organizational, verbal, communication and interpersonal skills. You must be able to work both independently and part of a research team, and be capable of obtaining a Home Office personal license if you do not already hold one.</div><br> <div>&#160;</div><br> <div>It is desirable that you have experience in cardiovascular research working with animal models, including surgical models, and in particular use of the mouse for lineage-tracing and in vivo studies.&#160; Experience of standard molecular cloning (recombineering), next generation sequencing and confocal imaging with computational methods including bioinformatics and image analysis software would be beneficial.</div><br> <div>&#160;</div><br> <div>You will be based in the Department of Physiology, Anatomy and Genetics, Sherrington Building,&#160; Parks Road, Oxford, OX1 3PT.</div><br> <div>&#160;</div><br> <div>The position is fixed term, funded by the Medical Research Council until 16/05/2025.</div><br> <div>&#160;</div><br> <div>Closing date for applications is <strong>Wednesday 1st June 2022.</strong></div><br> <div>&#160;</div><br> <div>Interviews are likely to be held w/c 13th June 2022.</div><br> <div>&#160;</div><br> <div><strong>Previous applicants need not apply.</strong></div><br> <div>&#160;</div><br> <div>Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.</div><br> <div>&#160;</div><br> <div>We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. &#8211; DPAG Statement of Inclusion</div> </div>

Post-doctoral Research Scientist in dopamine and astrocyte biology in health and Parkinson's disease

Closes: June 6, 2022, noon; salary: Standard Grade 7: £33,309 - £40,927

<div> <p></p><div><strong>Fixed term post until 18 April 2024</strong></div><br> <div>&#160;</div><br> <div>THIS IS A RE-ADVERTISEMENT, PREVIOUS APPLICANTS NEED NOT APPLY</div><br> <div>&#160;</div><br> <div>The Cragg Group at the University of Oxford are conducting an MRC-funded research project to explore the role of astrocytes in the regulation of striatal dopamine function in health and parkinsonism. We are now seeking to appoint a Postdoctoral Research Scientist with an interest in astrocyte biology to join the group and work as part of this exciting project.</div><br> <div>&#160;</div><br> <div>The successful candidate will develop, conduct, analyse and report on studies to elucidate dopamine transmission, its regulation and dysregulation by activity in astrocytes, related circuits and signalling molecules in mouse brain. The technical approaches involved will include detection of dopamine neurotransmission using fast-scan cyclic voltammetry, imaging of genetically encoded fluorescent neurotransmitter reporters, and/or whole cell electrophysiology, in brain slices in mouse models of Parkinson&#8217;s disease. The candidate will also collaborate on projects with the Cragg Group&#8217;s internal and external partners and when appropriate, undertake the training and supervision of other members of the Group. The candidate will be responsible for acquiring, analysing and interpreting scientific data, ensuring that the data are of the highest quality.</div><br> <div>&#160;</div><br> <div>In addition to having, or nearing completion of, a PhD/M.D. or equivalent qualification in a relevant discipline, candidates should have a promising track record of original research in their particular field of neuroscience. Candidates are also expected to have technical expertise in real-time electrochemical or electrophysiology recordings in brain slices, in neurosurgery, with rodents and to provide evidence of creative and critical thinking as applied to the delivery of a focused programme of research. Experience of studying astrocytes is desirable.</div><br> <div>&#160;</div><br> <div>The post holder will work in the Group led by Professor Stephanie Cragg, and will be based at the Department of Physiology, Anatomy and Genetics, Sherrington Building, Parks Road, Oxford, OX1 3PT.</div><br> <div>&#160;</div><br> <div>This is a full-time, fixed-term post available until 18 April 2024 funded by the MRC. Owing to the nature of this position, any offer of employment with the University will be subject to a satisfactory security screening.</div><br> <div>&#160;</div><br> <div>Informal enquiries can be addressed to Stephanie.cragg@dpag.ox.ac.uk.</div><br> <div>&#160;</div><br> <div>Closing date for applications is <strong>noon on Monday June 6th</strong></div><br> <div>Interviews are likely to be held <strong>between June 17th and 24th</strong></div><br> <div>&#160;</div><br> <div>Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.&#160;</div><br> <div>We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. &#8211; DPAG Statement of Inclusion&#160;</div><br> <div>&#160;</div> </div>